Wommack started preaching in 1969. He married his wife Jamie in 1972. Over the next six years, they led three small churches and had two sons, Joshua and Jonathan Peter.
In 1976, Andrew broadcast his first Gospel Truth radio program on a little country-and-western station in Childress, Texas. The Wommacks founded Andrew Wommack Ministries, Inc. in 1978 and moved their ministry to Colorado Springs in 1980.
With the exception of a few months, Wommack has been broadcasting the program ever since. Then in January 2000, he broadcast the first Gospel Truth television program on INSP Network. Response to the message was tremendous, and since then, DayStar Network and The Church Channel, and CTN Christian Television Network in the U.S., GOD TV in Europe and around the world, and several individual television stations have been added.
Wommack joined Trinity Broadcasting Network's lineup with his own daily radio and television show Gospel Truth with Andrew Wommack